Requires a referral from Psychiatry. Recently performed and published studies have shown a very low dose of ketamine infused over one hour have had significantly positive effects on clinical depression, especially towards suicidal feelings and anxiety. The results show a pretty immediate resolution of depression, immediately or a few hours. Ketamine is a medication that has been widely used in humans as an anesthetic since 1970. Ketamine is given as an IV infusion in a much smaller dose and shorter duration than required for anesthesia purposes.